US FDA pushes for new methods to replace animal testing in early drug studies

March 18 (Reuters) - The U.S. Food and Drug Administration on Wednesday issued a draft guidance to help companies reduce animal studies of experimental drugs and adopt newer methods, such as computer ...

FDA outlines plan to phase out animal testing in new draft guidance

The guidance clarifies what sponsors should consider when putting together an application for the validation of a NAM ...
pharmaphorum

FDA publishes advice on animal testing alternatives

New draft guidance from the FDA is urging pharma companies to accelerate efforts to transition from animal testing to ...
Fierce Biotech

FDA, NIH pledge more flexibility and $150M investment for animal testing alternatives

Health authorities in the U.S. are continuing their move away from animal testing in drug development, with the FDA signaling an openness to new approaches that haven’t been validated and the National ...
dvm360

Federal draft guidance focuses on alternative methods to animal testing

Officials with the FDA have released a draft guidance that aims to help drug developers validate new approach methodologies (NAMs) that can be used in place of animal testing. Based on human-centric ...
Hosted on MSN

FDA to eliminate unnecessary animal testing

(NewsNation) — The FDA is eliminating “unnecessary testing” on animals, according to Commissioner Marty Makary. He joined “Katie Pavlich Tonight” to make the announcement, sitting down with NewsNation ...
Applied Clinical Trials Online

FDA Issues Draft Guidance to Validate Non-Animal Testing Methods in Drug Development

The FDA has released a draft guidance outlining how drug developers can validate new approach methodologies (NAMs) as alternatives to animal testing in preclinical drug development. The guidance, ...
Healio

FDA efforts to reduce animal testing signal shift toward AI, organ-on-chip study methods

In April 2025, the FDA announced plans to shift biomedical research for monoclonal antibodies and other medications away from animal testing toward new approaches. One year later, much speculation ...

Feds keep Monkey Island on life support as animal testing debate rages

A federal health agency is spending $4.3 million to keep SC’s famous Monkey Island on life support while debate rages over ...
STAT

FDA and NIH announce more initiatives to reduce animal testing in drug development

HHS has made reducing animal testing a priority over the past year. In April 2025, the FDA announced it would phase out the animal testing requirement for monoclonal antibodies. A few months later, ...

Magnetic fields guide lab-grown blood vessels into precise patterns for drug testing

Animal studies often fail to predict human tissue responses to new drugs or newly developed therapies. Besides generating tremendous costs for clinical studies, it also raises significant ethical ...