Modeling the economic impact of a CIZ1B biomarker blood test for lung cancer screening in high-risk populations. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract ...

Cancer cells reprogramme their metabolism to support rapid proliferation, survival under stress and adaptation to fluctuating nutrient supplies. Central to this reprogramming is a shift towards ...

Colorectal cancer (CRC) progression critically depends on the tumor microenvironment. PLOD2, an enzyme involved in collagen biosynthesis, is highly expressed in many cancers. While it promotes CRC ...

Investigators led by Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how the metabolism of mitochondria supports ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital, published in Cell, ...

Researchers at the Federal University of São Paulo (UNIFESP) in Brazil have identified a molecule on the surface of cells that could be a promising therapeutic target against cancer. This molecule ...

The same genes could hold the key to regenerating cells in the ear and eye, according to a new mouse study from the USC Stem Cell laboratory of Ksenia Gnedeva, PhD, published in the Proceedings of the ...

Follistatin-344 has emerged as a molecule of growing interest within peptide research, particularly due to its intricate ...

Stem cells can self-renew and differentiate into a wide variety of cell types, making them critical components in embryonic development. In adults, stem cell populations, such as those in the ...

In a groundbreaking development, scientists have uncovered a type of immortal cell in laboratory settings, offering unprecedented potential for medical research and treatment. These cells, with their ...