Cell–cell junctions form the structural and functional backbone of multicellular tissues, coupling adhesive complexes with the actomyosin cytoskeleton to regulate barrier function, tissue remodelling ...
T cells expressing chimeric antigen receptors (CAR T) that target specific cancer antigens have revolutionized immunotherapy for hematological malignancies 1. However, no CAR T cell products are ...
A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in ...