Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

Study: Molecular and circuit determinants in the globus pallidus mediating control of cocaine-induced behavioral plasticity. Image Credit: Alex Mit / Shutterstock.com Ventral tegmental area dopamine ...

A new study reveals how cocaine use alters brain circuits tied to memory and reward, leaving the brain more vulnerable to relapse.

While scientists really do seem to love getting rats loaded on cocaine, a new study of rodents getting high on the lab's supply reveals intriguing new insights into how individuals respond differently ...

Experiencing multiple childhood traumas doesn't just increase the risk of a single addiction. A new study suggests it creates ...

I don’t drink anymore. I don’t smoke anymore.” He might have shrugged it off, but reports accumulated in his clinic and ...