Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Evidence is mounting that the wildly popular weight-loss medicines known as GLP-1s may also hold potential for treating addiction, and the field may be on the verge of obtaining desperately needed ...

New research suggests the weight-loss medications could be powerful tools in tackling substance use disorders.

What’s driving the permanent crisis of drug addiction? To express the ambient feeling that “things are getting worse,” there exists, of course, a meme. It plots iterations of a chart, and on its ...

A new study finds that popular GLP-1 drugs used to treat diabetes and obesity show new promise in fighting multiple substance use disorders. An analysis of electronic health records of more ...

Polysubstance use has become a defining feature of the U.S. overdose crisis in the past decade. While not every overdose involves multiple substances, a significant and growing proportion includes ...

PHILADELPHIA — When Justin Carlyle, 23, began experimenting with drugs a decade ago, he found himself part of a generation of young Americans caught in the devastating wave of harm caused by fentanyl ...