The study underscores the expanding role of computational modeling in biocatalysis research. By supporting early-stage evaluation and hypothesis testing, in silico methodologies may help reduce ...

The authors’ approach is deceptively simple: take an aldehyde dehydrogenase enzyme, which naturally converts aldehydes to acids, and get it to react with an amine instead of water. But actually making ...

Amide bonds are common in drugs because they are chemically stable, form readily and are biocompatible. They also help ...

This Collection supports and amplifies research related to SDG 12 - Responsible Consumption & Production. Biosynthesis and enzyme engineering is a dynamic field focused on harnessing and modifying ...

AI can help protein engineers optimize the transcription enzymes used to make mRNA-based vaccines and therapeutics, say the authors of a new study.

Researchers developed C28, an engineered polymerase that efficiently synthesizes RNA at near-natural speeds with high accuracy. Created through directed evolution, the enzyme also performs reverse ...

A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl ...

The research findings were featured on the cover of Nature Catalysis and highlighted in Nature, as well as in collections in Nature Chemical Engineering in 2022 and 2023. A joint research team, led by ...

Monrovia, CA, April 10, 2025 (GLOBE NEWSWIRE) -- Today, eXoZymes Inc. (NASDAQ: EXOZ) (“eXoZymes”) - a pioneer of AI-engineered enzymes that can transform sustainable feedstock into nutraceuticals, ...

Fructooligosaccharides (FOS) are functional, low-calorie carbohydrates renowned for their prebiotic properties and widespread applicability in the food and pharmaceutical industries. Current ...

From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But as ...