For decades, geneticists have known that most common illnesses are not caused by a single rogue gene but by intricate constellations of DNA variants acting together in specific cells. Now a new ...
Researchers led by Min Zhang and Dabao Zhang of the University of California, Irvine's Joe C. Wen School of Population & Public Health have created the most detailed maps to date showing how genes ...
A variety of techniques are used to map the cellular state space in single-cell RNA-sequencing (scRNA-seq) analysis, including dimensionality reduction approaches PCA, UMAP and PHATE 1,2,3. These ...
Researchers at the University of California San Diego have completed a massive genetic study that identifies key biological drivers of cocaine addiction, uncovering a potential new target for ...
Epigenetic modifications influence gene expression levels, impact organismal traits, and play a role in the development of diseases. Therefore, variants in genes involved in epigenetic processes are ...
Scientists at the University of California San Diego have reported the results of a genome-wide association study in rats that identified key biological drivers of cocaine addiction. Using a ...