Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful tool to record and dissect gene expression of individual cells in tissues. Compared to bulk RNA-seq, where RNAs from all cells in a ...

Pooled genome editing combined with single-cell RNA sequencing—commonly known as Perturb-seq—has transformed the ability to interrogate genome function. However, whole-transcriptome single-cell RNA ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the technology has both laid the foundation for building cell atlases and allowed ...

The rapid advancement of single-cell and single-nucleus RNA sequencing (sc/snRNA-seq) has opened unprecedented windows into cellular diversity, yet existing methods for multiplexing samples struggle ...

Chimeric antigen receptor T cell (CAR-T) therapy is considered one of the landmark achievements of modern medicine. The therapy involves harvesting a patient’s own immune cells, genetically ...

The heart and brain are among the earliest and most metabolically demanding organs in human development. Though historically studied in isolation, both ...

Scientists can peer into cells to get a limited view of their activity using microscopes and other tools. However, cells and the molecular events within them are dynamic, and developmental processes, ...

Plasmidsaurus has launched a new RNA-Seq service for Illumina short read applications, bringing the same approach they use for plasmid sequencing to gene expression analysis. Attendees at this week’s ...