Combined epigenetic and immune checkpoint therapy altered the tumour microenvironment in platinum-resistant ovarian cancer.

An interdisciplinary multi-center research team led by the LKS Faculty of Medicine (HKUMed) and Faculty of Dentistry at the ...

An interdisciplinary multi-centre research team led by the LKS Faculty of Medicine (HKUMed) and Faculty of Dentistry at the ...

Throughout the entire process of cancer aetiology, progression and metastasis, the microenvironment of the local host tissue can be an active participant. Invasion occurs within a tumour–host ...

A silicon-based nanothrombolytic combines clot dissolution with local microenvironment regulation, enhancing safety and efficacy in thrombotic disorders.

MILAN — Is chronic lymphocytic leukemia (CLL) progression primarily driven by genetic mutations or by external cues from the tumor microenvironment? Despite major strides in targeted therapies, CLL ...

There is growing evidence that inflammation is a central and reversible mechanism through which obesity promotes cancer risk and progression. Locally, hyperadiposity is associated with altered adipose ...

Thrombotic disorders—such as ischemic stroke, heart attack, pulmonary embolism, and deep vein thrombosis—are principal contributors to global mortality. However, conventional thrombolytic therapies ...

The tumor microenvironment is a battleground where infiltrating immune cells either subdue or promote a cancer, all while cancer cells try to dampen the body’s defenses. 1,2 Scientists have studied ...

A large multiomics study of brain metastases identified four molecular subtypes shaped by the brain microenvironment, not ...