New polygenic risk scores can more accurately predict obesity, type 2 diabetes, and downstream complications such as heart attack and stroke.

Allelica, a leader in genomic risk assessment for common diseases, announced today that polygenic risk scores (PRS) have been recognized as a risk-enhancing factor in the 2026 American College of ...

Type 2 diabetes (T2D) and obesity are metabolic conditions with many causes, including overlapping and distinct genetic features. A polygenic risk score (PRS) can capture multiple genetic risk factors ...

Atrial fibrillation (AF) is a common arrhythmia associated with increased risk of stroke, heart failure and mortality. Advances in genomic research have revealed a complex genetic architecture ...

Biologically enriched MetPRS has the potential to add an extra layer of information to metabolic disease prediction and management approaches.

Please provide your email address to receive an email when new articles are posted on . Researchers said common risk variants help explain why epilepsy occurs in some family members and not others.

Genetic variants associated with mental disorders do not have a significant influence on methylphenidate response in ADHD cohorts.

The figure illustrates the major categories of genes that may influence susceptibility to dental caries, organized by their biological functions and pathways. These groups include: (1) Enamel ...