Super-resolution microscopy methods are essential for uncovering the structures of cells and the dynamics of molecules. Since researchers overcame the resolution limit of around 250 nanometers (while ...

Super-resolution microscopy, or nanoscopy, enables the use of fluorescent-based molecular localization tools to study molecular structure at the nanoscale level in the intact cell. Analysis of ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

As an indispensable tool for observing the microcosmos, optical microscopy has boosted the development of various fields, including biology, medicine, physics, and materials. However, optical ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

Example of super-resolution microscopy: The image shows how the Discrete Molecular Imaging (DMI) technology visualizes densely packed individual targets that are just 5 nanometer apart from each other ...

Latest super-resolution microscopy methods now achieve an optical resolution in the range of a few nanometers. This corresponds to a resolution in the range of the size of cellular molecules. However, ...

What is Structured Illumination Microscopy? Structured Illumination Microscopy (SIM) is a super-resolution fluorescence microscopy technique that allows for imaging beyond the diffraction limit of ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

Researchers have developed an innovative method to simultaneously track rapid dynamic processes of multiple molecules at the molecular scale. Researchers at LMU have developed an innovative method to ...