Gangliosides, a class of sialic acid containing complex glycosphingolipids are characteristic components of neuronal cells. Neuronal ganglioside profiles vary in different regions of the brain and ...

Analytical validation of the Oncomine Immune Response Research Assay (OIRRA) in a CLIA and CAP regulated laboratory for formalin fixed, paraffin embedded (FFPE) solid tumor specimens. Effect of the ...

In a recent study posted to the bioRxiv* preprint server, researchers explored sphingosine kinases (SK) inhibitors and characterized the role of SKs in Ebola virus (EBOV) entry. Study: Sphingosine ...

Sphingolipids are important biological molecules, a class of lipids that have a backbone of sphingoid bases including sphingosine (aliphatic amino alcohol) or another structurally similar compound. In ...

The pathway by which blood cells release the important signalling lipid, sphingosine-1-phosphate (S1P), has now been discovered. They showed that the membrane protein Mfsd2b is responsible for ...

Measuring circulating blood levels of a specific lipid, sphingosine, allows clinicians to predict whether COVID-19-positive patients will go on to develop symptoms or remain asymptomatic. Researchers ...

Identification and external validation of clinical-molecular features to predict benefit from oxaliplatin reintroduction/rechallenge in patients with refractory ...