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This is mostly based on the proportion of type 2 fibers in the muscle, as well as their level of voluntary activation. PMID 4120482 What should you do with this information? Recovery is still pretty personal and tracking volume/progression is still the best approach, but this can be an easy sense-check to try and spot something obviously wrong. Doing more sets for biceps than for quads? Good chance either of them doesn’t have the right volume
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Training to failure is a physiological trap. While it may feel like you’re working harder, your muscle fibers have actually entered Product Inhibition. This is where Inorganic Phosphate and Hydrogen Ions flood the muscle fiber and physically prevent the Myosin heads from releasing their own phosphate. This traps the fibers in a weak-binding state, preventing the transition to the strong-binding state and causing a significant drop in single-fiber tension. Simultaneously, the rising acidity reduc
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